Oral Formulation Researchers

Oral Formulation Researchers work in the Department of Oral Formulation Research in Global Research Technologies. Currently, most of our therapeutic peptides and proteins are injectable, but we aim to make more oral products available to our patients in the future. Our Oral Formulation Researchers play a key role in Novo Nordisk’s R&D strategy, as they are responsible for developing new oral peptide and protein formulations that will feed the R&D pipeline in all our therapeutic areas.

Tina Pedersen

Oral Formulation Researchers are responsible for identifying new, innovative oral drug delivery systems for the oral drug project portfolio. Specifically, they formulate therapeutic peptides and proteins into orally available products, including solid dosage forms and oral devices. They are also responsible for solid-state characterisation and analysis of both drug product intermediates and the final drug product.

Formulation researchers work very early in the R&D value chain. They perform early research activities, identify oral formulations for our therapeutic peptides and proteins, and find compositions and processes by which these formulations can be made. Once a suitable formulation has been identified, tested, and found to fulfil the given target product profile, the composition and process are transferred to CMC Development, where it will be further upscaled and manufactured for clinical trials. An oral formulation researcher needs to have an innovative mind, a can-do attitude, good communication skills, and a broad scientific background. A deep insight into the gastrointestinal tract is a strong asset, since it is the target organ of most of our oral formulations.

A formulation researcher typically holds an M.Sc. or a Ph.D. in Life Sciences (pharmaceutical sciences, biomedical engineering, or other relevant disciplines), depending on the seniority level of the position. Experience and knowledge of oral (solid) dosage forms or oral device technology covering pharmaceutical formulation expertise, solid-state characterisation and analysis are required. Most of our more experienced colleagues have a track record of publications in the field of oral drug delivery.

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Listen to Tina Pedersen, Head of Department, and Jorrit Water, Principal Scientist introduce the Oral Formulation Research Department. The main purpose of the department is to formulate therapeutic peptides and proteins into oral dosage forms and oral devices.?

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Jian Xiong Wu is a Senior Research Scientist at the Oral Formulation Research department in R&D. He joined Novo Nordisk because he wanted to see his ideas come to life, he wanted to feel his work was making a difference to patients. Listen to Jian explain how his work motivates him and how he experiences the team work at Novo Nordisk.


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Oral Protein Formulation

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